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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
14.24
Human Site:
S121
Identified Species:
24.1
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
S121
Q
T
S
V
E
E
C
S
Q
K
G
C
L
A
L
Chimpanzee
Pan troglodytes
XP_514393
802
89426
V81
V
F
L
A
S
L
L
V
L
I
E
P
V
A
A
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
S121
Q
S
S
V
E
E
C
S
Q
K
G
C
L
A
L
Dog
Lupus familis
XP_535404
889
99260
S140
Q
T
S
V
E
E
C
S
Q
K
G
C
L
A
L
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
S121
Q
T
S
V
E
E
C
S
Q
K
G
C
L
A
L
Rat
Rattus norvegicus
P51799
803
88712
P82
H
T
F
P
K
E
I
P
H
N
E
K
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
M128
Y
E
A
V
K
W
M
M
V
F
A
I
G
V
C
Chicken
Gallus gallus
XP_417644
868
97172
E120
S
S
V
E
E
C
T
E
R
G
C
L
A
L
S
Frog
Xenopus laevis
Q9W701
689
76782
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
G120
V
E
E
C
S
E
N
G
C
L
A
L
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
P82
L
N
T
E
E
I
L
P
G
A
T
N
F
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
G40
V
F
I
N
Y
F
V
G
L
L
S
N
W
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
Y71
R
G
K
L
Y
V
G
Y
Y
V
A
V
K
W
F
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L58
V
D
S
D
R
E
F
L
N
S
K
Y
R
H
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
6.6
93.3
100
N.A.
100
20
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
26.6
N.A.
20
20
0
13.3
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
8
22
0
8
36
8
% A
% Cys:
0
0
0
8
0
8
29
0
8
0
8
29
0
0
8
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
8
15
43
50
0
8
0
0
15
0
0
0
0
% E
% Phe:
0
15
8
0
0
8
8
0
0
8
0
0
8
0
8
% F
% Gly:
0
8
0
0
0
0
8
15
8
8
29
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
8
8
0
0
8
0
8
0
0
0
% I
% Lys:
0
0
8
0
15
0
0
0
0
29
8
8
8
8
0
% K
% Leu:
8
0
8
8
0
8
15
8
15
15
0
15
36
29
43
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
8
8
0
15
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
15
0
0
0
8
0
0
0
% P
% Gln:
29
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% R
% Ser:
8
15
36
0
15
0
0
29
0
8
8
0
8
0
22
% S
% Thr:
0
29
8
0
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
29
0
8
36
0
8
8
8
8
8
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% W
% Tyr:
8
0
0
0
15
0
0
8
8
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _